Volume 2, Issue 2, March 2016, Page: 11-15
LncRNAs: The Ideal Composer of the Melody for Life
Qingyu Cheng, CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
Shengwei Ke, CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
A. R. Ghanam, CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China; Collage of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
Xiaoyuan Song, CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
Received: May 18, 2016;       Accepted: Jun. 6, 2016;       Published: Jun. 30, 2016
DOI: 10.11648/j.bs.20160202.11      View  4583      Downloads  150
Abstract
Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.
Keywords
Long Noncoding RNA, Human Diseases, Epigenetic, Transcription, Post-Transcription
To cite this article
Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song, LncRNAs: The Ideal Composer of the Melody for Life, Biomedical Sciences. Vol. 2, No. 2, 2016, pp. 11-15. doi: 10.11648/j.bs.20160202.11
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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